TehHatFactory at 801 Minnesota #8 is very accessible and offers plenty of parking. TehSpace is open from 10am-6pm Monday thru Friday, or when SanFranciscoAnchors are present.
Public transit
You can take the Muni Bus #22 all the way down to 20th and Tennessee. Corbett Bus #37 also stop in the area. Use 511 Trip Planner to schedule your travel.
The Caltrain stop at 22nd street is within 3 blocks. Use iamcaltrain.com to plan your trip.